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Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (QUIP) (Long Form)
Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (QUIP) (Long Form)
| Availability |
Please email the author for information about obtaining the instrument: Dr. Daniel Weintraub, weintrau@mail.med.upenn.edu
Permission for use should be sought from the author, Dr. Weintraub. The University of Pennsylvania holds the copyright to the QUIP.
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| Classification |
Supplemental - Highly Recommended: Parkinson's Disease (PD)
Recommendations for use: Indicated for studies assessing impulse control or behavioral disturbances in PD as one of the primary outcomes or in studies that need to assess a broader spectrum of ICD.
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| Short Description of Instrument |
The Questionnaire for Compulsive-Disorders in Parkinson's Disease (QUIP) is a self-rated (patient and informant) screening instrument developed and validated for the detection of ICDs and related behaviors in PD. Patients are asked structured questions for the most common ICDs reported in PD. There are full and abbreviated versions of the instrument. The long form contains 5 questions for each of the ICDs plus additional questions for other impulse control behaviors.
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| Comments/Special Instructions |
The QUIP was developed and validated for PD. It has been validated on DSM-IV-TR criteria and criteria for other PD-specific behaviors. It includes PD population specific impulse control behaviors that are not present in the general population (e.g., punding). This questionnaire has been translated into several languages. It is useful for diagnostic screening.
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| Scoring and Psychometric Properties |
Scoring: The QUIP has 3 sections: Section 1 assesses four ICDs (involving gambling, sexual, buying, and eating behaviors), Section 2 other compulsive behaviors (punding, hobbyism, and walkabout), and Section 3 compulsive medication use. 30 total questions
Psychometric Properties: high discriminant validity for each disorder (AUC) pathological gambling = 0.95, hyper sexuality = 0.97, compulsive buying = 0.87, compulsive eating = 0.88, punding = 0.78, hobbyism = 0.93, walkabout = 0.79, high negative predictive values, low positive predictive values so positive screen should be followed by clinical interview, agreement between patient and informant report is moderate k = 0.41
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| Rationale/Justification |
Strengths: developed and validated in PD cohorts, self-rated and brief, individual subscales were validated against the diagnostic standard semi-structured interviews for each ICD, includes a broad range of ICDs.
Weaknesses: risk of overidentification as up to 40% will have positive QUIP without an ICD diagnosis, limited sensitivity for punding and walkabout, limited validity for compulsive medication use, does not evaluate the severity of ICDs, poor agreement between patient and informant ratings in some studies.
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| References |
Key Reference:
Weintraub D, Hoops S, Shea JA, Lyons KE, Pahwa R, Driver-Dunckley ED, Adler CH, Potenza MN, Miyasaki J, Siderowf AD, Duda JE, Hurtig HI, Colcher A, Horn SS, Stern MB, Voon V. Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's disease. Mov Disord. 2009 Jul 30;24(10):1461-7.
Additional Reference:
Papay K, Mamikonyan E, Siderowf AD, Duda JE, Lyons KE, Pahwa R, Driver-Dunckley ED, Adler CH, Weintraub D. Patient versus informant reporting of ICD symptoms in Parkinson's disease using the QUIP: validity and variability. Parkinsonism Relat Disord. 2011 Mar;17(3):153-5.
Document last updated August 2022
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